Research: Different risk factors distinguish ME/CFS from severe fatigue
Severe Fatigue is not the same as ME/CFS US researchers led by Prof Komaroff found that severe fatigue was much more common than ME/CFS in a large group of…
Research: Gut dysfunction found in ME/CFS
Gut bacteria could have answers for ME/CFS Two separate US studies have found significant differences in the gut microbiomes of people with ME/CFS compared to healthy people, although it…
Research: Metabolomic evidence for peroxisomal dysfunction in ME/CFS
Metabolomic evidence for peroxisomal dysfunction in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Research conclusion: Our findings provide the first metabolomic evidence of peroxisomal dysfunction, and are consistent with dysregulation of lipid…
Diagnostic test research: Orthostatic challenge causes the same responses in Long COVID & ME/CFS
Orthostatic challenge causes distinctive symptomatic, hemodynamic and cognitive responses in Long COVID and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, by Suzanne D Vernon, Sherlyn Funk, Lucinda Bateman, Gregory J Stoddard, Sarah Hammer,…
Research review: Redox imbalance links COVID-19 & ME/CFS
Redox imbalance links COVID-19 and myalgic encephalomyelitis/chronic fatigue syndrome, by Bindu D Paul, Marian D Lemle, Anthony L Komaroff, Solomon H Snyder in PNAS August 24, 2021 118 (34); [doi.org/10.1073/pnas.2024358118]…
Viewpoint: ME/CFS: when suffering is multiplied
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: when suffering is multiplied, by Anthony L Komaroff in Healthcare 2021, 9(7), 919 [doi.org/10.3390/healthcare9070919] 20 July 2021 (This article belongs to the Special Issue ME/CFS – the Severely…
Insights from ME/CFS may help unravel the pathogenesis of post-acute COVID-19 syndrome
Insights from Myalgic Encephalomyelitis/Chronic Fatigue Syndrome may help unravel the pathogenesis of post-acute COVID-19 syndrome, by Anthony L Komaroff, W Ian Lipkin in Trends in Molecular Medicine, 7 June 2021…
Plasma proteomic profiling suggests an association between antigen driven clonal B cell expansion & ME/CFS
Plasma proteomic profiling suggests an association between antigen driven clonal B cell expansion and ME/CFS, by Milica Milivojevic, Xiaoyu Che, Lucinda Bateman, Aaron Cheng, Benjamin A Garcia, Mady Hornig, Manuel Huber,…
Advances in understanding the pathophysiology of CFS
Advances in understanding the pathophysiology of Chronic Fatigue Syndrome, by Anthony L Komaroff in JAMA [Preprint July 5, 2019] Viewpoint extracts: When does an illness become a disease? When the underlying…
Insights into ME/CFS phenotypes through comprehensive metabolomics
Research abstract: Insights into myalgic encephalomyelitis/chronic fatigue syndrome phenotypes through comprehensive metabolomics, by Dorottya Nagy-Szakal, Dinesh K. Barupal, Bohyun Lee, Xiaoyu Che, Brent L. Williams, Ellie J. R. Kahn, Joy…